An efficient and economical method of synthesis for Ivacaftor: A CFTR modulator.
Temp 4
DST
March 27, 2023
None
None
Cystic fibrosis
In vitro study
Quantitative data
• To develop the process chemistry & optimize the process of synthesis for Ivacaftor and Lumacaftorunder patent to make it affordable for Cystic Fibrosis patients in India.
• To apply eco-friendly synthetic approaches in the process chemistry.
• To characterize the synthesized product using spectral analysis.
• To perform profiling for any impurity produced during the synthesis.
Ivacaftor, CFTR modulator, Lumacaftor, Cystic Fibrosis,
None
None
Dr. P Senthil Kumar/None/Karpagam Academy of Higher Education, Coimbatore