Genetic Characterization And Clinical Correlates Of Polymicrogyria Syndromes
33/11/2019-TF/Rare/BMS
ICMR
Aug. 17, 2020
Aug. 16, 2023
Three Year
Polymicrogyria Syndromes
In silico and genetic studies
Quantitative data
Neuroimaging & WES of PMG samples. Identification of genetic variants associated with each type of PMG. In silico prediction of the functional impact of genetic variants
Cortical folding, gyral pattern, polymicrogyria, neuroimaging, whole exome sequencing, gene expressi
The study show that phenotypically diverse PMG syndromes share a common genetic background. The outcomes could help to improve the diagnosis, including prenatal diagnosis, & treatment of PMG, & to assist with genetic counseling
24,71,604/-
Dr. Anitha Ayyappan pillai/None/Department of Neurogenetics (ICCONS) ,Kerala